Cell 2013, 154:1269–1284 PubMedCrossRef 8 Nisman B, Kadouri L, A

Cell 2013, 154:1269–1284.PubMedCrossRef 8. Nisman B, Kadouri L, Allweis T, Maly B, Hamburger T, Gronowitz S, Peretz T: AZD6244 datasheet Increased proliferative background in healthy women with BRCA1/2 haploinsufficiency is associated with high risk for breast cancer. Cancer Epidemiol Biomarkers Prev 2013, 22:2110–2115.PubMedCrossRef 9. Nowsheen S, Cooper T, Stanley JA, Yang ES: Synthetic lethal interactions between EGFR and

PARP inhibition in human triple negative breast cancer cells. PLoS One 2012, 7:e46614.PubMedCentralPubMedCrossRef 10. Burga LN, Tung NM, Troyan SL, Bostina M, Konstantinopoulos Fosbretabulin cost PA, Fountzilas H, Spentzos D, Miron A, Yassin YA, Lee BT, Wulf GM: Altered proliferation and differentiation properties of primary mammary epithelial cells from BRCA1 mutation carriers. Cancer Res 2009, 69:1273–1278.PubMedCentralPubMedCrossRef 11. Bi FF, Li D, Yang Q: Promoter hypomethylation, especially around the E26 transformation-specific

motif, and increased expression of poly (ADP-ribose) LGX818 manufacturer polymerase 1 in BRCA-mutated serous ovarian cancer. BMC Cancer 2013, 13:90.PubMedCentralPubMedCrossRef 12. Szlosarek PW, Grimshaw MJ, Kulbe H, Wilson JL, Wilbanks GD, Burke F, Balkwill FR: Expression and regulation of tumor necrosis factor alpha in normal and malignant ovarian epithelium. Mol Cancer Ther 2006, 5:382–390.PubMedCrossRef 13. Varley KE, Gertz J, Bowling KM, Parker SL, Reddy TE, Pauli-Behn F, Cross MK, Williams BA, Stamatoyannopoulos JA, Crawford GE, Absher DM, Wold BJ, Myers RM: Dynamic DNA methylation across diverse human cell lines and tissues. Genome Res 2013, 23:555–567.PubMedCentralPubMedCrossRef 14. Burga LN, Hu H, Juvekar A, Tung NM, Troyan SL, Hofstatter EW, Wulf GM: Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents Megestrol Acetate estrogen receptor-negative cancers in BRCA1-mutant mice. Breast Cancer Res 2011, 13:R30.PubMedCentralPubMedCrossRef

15. Samani AA, Yakar S, LeRoith D, Brodt P: The role of the IGF system in cancer growth and metastasis: overview and recent insights. Endocr Rev 2007, 28:20–47.PubMedCrossRef 16. Dacheux E, Vincent A, Nazaret N, Combet C, Wierinckx A, Mazoyer S, Diaz JJ, Lachuer J, Venezia ND: BRCA1-Dependent Translational Regulation in Breast Cancer Cells. PLoS One 2013, 8:e67313.PubMedCentralPubMedCrossRef 17. Calvo V, Beato M: BRCA1 counteracts progesterone action by ubiquitination leading to progesterone receptor degradation and epigenetic silencing of target promoters. Cancer Res 2011, 71:3422–3431.PubMedCrossRef 18. Katiyar P, Ma Y, Riegel A, Fan S, Rosen EM: Mechanism of BRCA1-mediated inhibition of progesterone receptor transcriptional activity. Mol Endocrinol 2009, 23:1135–1146.

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