The last issue till now, which arose our interest were laminopathies in children, i.e. congenital dystrophy, restrictive dermopathy and progeria, which lead us to problem of premature aging. Madej-Pilarczyk described a large family affected by overlapping Entinostat chemical structure syndrome of progeria and restrictive dermopathy,

associated with homozygous mutation in LMNA gene (44). Our next step would be continuation of present work with special attention on the role of laminopathies in development and in normal and premature aging”. Conclusions Fruitful discussion during all the meeting clarified Inhibitors,research,lifescience,medical different points of view, and constructively resulted in a proposal for a wide European collaboration. The interdisciplinary approach

to laminopathies was highly encouraged. This was an enjoyable and fruitful workshop that will lead to new collaborations and will contribute significantly to the improvement of future therapeutic perspectives in laminopathies. List Inhibitors,research,lifescience,medical of participants Nicola Carboni, Department of Public Health, Molecular and Cellular Medicine, University of Cagliari, Italy Krystyna Domańska-Janik, Neurorepair Department, Mossakowski Medical Research Centre, Warsaw, Poland Inhibitors,research,lifescience,medical Anna Fidziańska, Neuromuscular Unit, Mossakowski Medical Research Center, Polish Academy of Science, Warsaw, Poland Roland Foisner, Max F Perutz Laboratories, Medical University Vienna, Vienna, Austria Yosef Gruenbaum, Department of Genetics, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Israel Irena Hausmanowa-Petrusewicz, Inhibitors,research,lifescience,medical Neuromuscular Unit, Mossakowski Medical Research Center, Polish Academy of Science, Warsaw, Poland Chris Hutchison, School of Biological and Biomedical Sciences, Durham University, UK Agnieszka Madej-Pilarczyk, Neuromuscular Unit, Mossakowski Medical Research Center, Polish Academy of Science, Warsaw, Poland Michal Marchel, 1st Department of Cardiology, Medical University of Warsaw, Warsaw, Poland Grzegorz

Opolski, 1st Department of Cardiology, Inhibitors,research,lifescience,medical Medical University of Warsaw, Warsaw, Poland Luisa Politano, Cardiomyology and Medical Genetics, Second University of Naples, Naples, Italy Monika ADP ribosylation factor Puzianowska-Kuznicka, Department of Human Epigenetics, Mossakowski Medical Research Centre, Warsaw, Poland; Department of Geriatrics and Gerontology, Medical Centre of Postgraduate Education, Warsaw, Poland Ryszard Rzepecki, Laboratory of Nuclear Proteins and 2Laboratory of Cytobiochemistry, Department of Biotechnology, University of Wrocław, Poland Acknowledgements Dr. Foisner work is funded by grants of the Austrian Science Fund (FWF).
Mutations on the LMNA gene are responsible for an heterogeneous group of diseases. Overlapping syndromes related to LMNA gene alterations have been extensively reported.