Dynamic mechanical analysis testing showed that the addition of epoxy resin induced the glass-transition temperature of PA6 and the styrene-co-acrylonitrile copolymer phase to shift to higher temperatures due to the chemical reactions between
PA6, ABS-g-MA, and epoxy resin. The scanning electron microscopy results indicated that the ABS-g-MA copolymer dispersed into the PA6 matrix uniformly and that the phase morphology of the PA6/ABS-g-MA blends did not change with the addition of the epoxy resin. Transmission electron microscopy showed that the epoxy resin did not change the deformation mechanisms of the PA6/ABS-g-MA blends. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 121: 909-915, 2011″
“Background: Plasmodium falciparum merozoites are free invasive forms that invade host erythrocytes in iterative cycles in the presence JNJ-26481585 in vitro of different arms of the immune ISRIB molecular weight system. Variant antigens are known to play a role in immune evasion and several gene families coding for variant antigens have been identified in P. falciparum. However, none of them have been reported
to be expressed on the surface of merozoites.
Methods: Flow cytometry, immunofluorescence microscopy, and immunoblotting assays were performed to assess surface exposure, membrane association and stage specific expression of the STEVOR family of variants proteins, respectively.
Results: Using a polyclonal antibody (anti-PFL2610w) with a broad specificity towards different STEVOR variants, the STEVOR proteins were identified on the surface of non-permeabilized/non-fixed merozoites in flow cytometry assays. Anti-PFL2610w antibody showed that several STEVORs were expressed in the trophozoite stage of the parasite but only one variant was integrated into the merozoite
membrane. Moreover, this antibody failed learn more to identify STEVORs on the surface of the parent schizont infected erythrocytes (IE) although they were readily identified when schizont IE were permeabilized.
Conclusions: These data suggest for a role for STEVOR in immune evasion by P. falciparum merozoites to allow successful invasion of erythrocytes. Additionally, the expression of STEVORs in the schizont stage may only represent a step in the biogenesis process of the merozoite surface coat.”
“Migraine (in particular with aura) is a risk factor for cerebrovascular disease; the relative risk of stroke in migraineurs is about twofold, and increases with the coexistence of female gender, cigarette smoking and old-preparation contraceptive use. The mechanisms of the increased risk are not completely understood, and the absolute risk of stroke is low; yet, migraineurs have to be advised on how to reduce the risk for primary prevention of stroke.”
“A new thermally conductive photoresist was developed.