A score was calculated for both knowledge and practice. These scores were dichotomized into less than median score (poor) and more than median score (good). 244 students were invited to participate. Results: Of the 244 students, 220 (90.2%) accepted to participate. Of the 9 knowledge questions about universal precautions, 7 were answered correctly by more than 60% (range 64.8-90.4) of the Ruboxistaurin students. All questions regarding the practice of universal precautions

were answered correctly by over 60% (range 61.8-96.4) of the students. The prevalence of poor knowledge was 38.2% (84/220) and poor practice was 27.7% (61/220). Grade point average was significantly (p = 0.008) associated with the knowledge status of the respondents; however, it was not significantly associated (p = 0.397) with practice of universal precautions. Furthermore, neither the knowledge status nor any of the sociodemographic variables

were significantly associated with the practice of universal precautions. Conclusions: A substantial number of students of the Faculty of Medicine, Kuwait University, in their clinical years appeared to have poor level of both knowledge and practice of universal precautions. Efforts are needed to optimize the level of knowledge and practice among students to minimize the risk of preventable infections. Copyright (C) 2012 S. Karger AG, Basel”
“1,2,3,4-Tetrahydro-beta-carbolines (TH beta Cs) are a pharmacologically important group of compounds belonging to the indole alkaloids. C1-Substituted optically active TH beta Cs have been the target of extensive synthetic efforts due to the presence of the scaffold

in numerous natural products and synthetic Belinostat Epigenetics inhibitor targets. This review briefly summarizes the methods to obtain the C1 stereocenter and concentrates on evaluating the pharmacological importance of optically active C1-substituted TH beta Cs, including their PDE5-inhibitory, antimalarial, antiviral and antitumor activities.”
“Purpose: We compared the long-term success of desmopressin sublingual lyophilisate formulation and enuretic alarm therapy in children with primary learn more monosymptomatic nocturnal enuresis, and determined predictive factors for treatment success. Materials and Methods: A total of 142 children with primary monosymptomatic nocturnal enuresis were randomized to receive treatment consisting of desmopressin or enuretic alarm for 6 months. Treatment compliance and response were reviewed monthly in each patient using a 30-day bed-wetting diary. Outcomes were assessed according to International Children’s Continence Society criteria, and success rates at 6 and 12 months were compared for desmopressin and enuretic alarm. Additional intention to treat analyses were performed, considering cases with missing data as failures. Possible demographic factors predicting success were investigated by logistic regression analysis. Results: Overall 4 children (5.2%) in the desmopressin group and 20 (30.