Conclusion ECT has proven to be a safe and efficacious therapy fo

Conclusion ECT has proven to be a safe and efficacious therapy for the local control of soft tissue neoplasms in companion animals, and its effectiveness is especially strengthened when used in an adjuvant fashion through the generation of trains of biphasic pulses [15, 21–37, 39–41, 43]. ECT is currently being assayed for different spontaneous tumors in companion animals showing promising results and identifying patterns of response and clinical [25–27]

as well as histopathological prognostic factors [31]. Further studies are currently ongoing to evaluate Selleckchem PFT�� new drugs and delivery systems to improve the responses obtained so far, in particular mitoxantrone is a drug that is showing considerable promise [43], also in view of its future applications to human patients. Acknowledgements This work has been supported by “”Grant 2008″” of the Italian Ministry of Health and by a “”AiCC”" Grant to E.P.S and G.C., and by a

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