Materials and methods: The computed tomography planning scans of
89 patients with adenocarcinoma of the prostate treated with conformal radiotherapy were reviewed. All patients had three gold seed fiducial markers implanted into the prostate before planning computed tomography. About one in five patients had repeat computed tomography because their rectum was judged to be too large at the time of the first planning computed tomography. Rectal distension was assessed on planning computed tomography using outlines following European Organization for Research and Treatment of Cancer guidelines by Selleckchem SHP099 measuring the rectal volume, the average cross-sectional area and the mean anterior-posterior
diameter of the rectum. Daily kV images were obtained before and after treatment delivery Selleckchem INCB028050 to determine positional matching of the fiducial markers in the superior-inferior, anterior-posterior and right-left dimensions.
Results: In total, 2860 pre -and post-treatment daily kV image pairs were obtained of 89 patients (average 32.1 image pairs per patient). The median rectal cross-sectional area was 7.3 cm(2) (range 2.8-17. 1), the median rectal volume was 54.8 cm(3) (range 20.9-128.2), and the median anterior-posterior rectal diameter was 3.03 cm (range 1.58-8.30). Unifactor linear regression models showed no statistically significant relationship between intra-and interfraction prostate stability and rectal volume on planning computed tomography.
Conclusions: No statistically significant relationship between recta[ distension on planning GSK1838705A computed tomography and the intra-and interfraction stability of the prostate gland was identified if patients with a large rectal volume were rescanned for planning. Stillie, A. L. et al. (2009). Clinical Oncology 21, 760-767 (C) 2009 The Royal College of Radiologists. Published by Elsevier
Ltd. All rights reserved.”
“Barium titanate (BT) and montmorillonite (MMT) nanoparticles were covalently-bonded by organically modifying the particle surfaces and chemically reacting them in solution. These integrated two-material hybrid inorganic nanofillers were subsequently dispersed in epoxy resin and nanocomposites were obtained at several weight fractions. The inorganic component consisted of well dispersed BT spherical nanoparticles that are surrounded by attached layered MMT nanoplatelets, with the latter having the ability to react with the epoxy matrix. The thermodynamic properties of the glass transition process, the macroscopic mechanical properties of the nanocomposites, and the dynamics of the polymer segments at the inorganic interfaces, all indicate that this filler configuration enhances the polymer-ceramic interfaces.