Postoperative pain rating scales (0 to 10) were used to determine efficacy.
Results: Mean followup was 20.3 months (range 1 to 102 months) and complete,
durable relief was noted in 67 (71%) testicular units, partial relief in 17 (17%), and unchanged in 11 (12%). No patients reported worse pain. Complications included testicular atrophy without hypogonadism in 2 patients, superficial wound infection in 2, hydrocele in 2 and an incisional hematoma in 1.
Conclusions: Microsurgical denervation of the spermatic cord is a minimally invasive, effective and durable management R428 option for treatment of chronic orchialgia refractory to medical management, preserving the physiological function and psychological role of the testes.”
“Purpose: To our AZD9291 clinical trial knowledge the most effective treatment in patients with renal stones containing calcium phosphate remains unknown. An inverse correlation exists between calcium phosphate stone composition and the stone-free rate of shock wave lithotripsy. It is unknown whether this is due to treatment type (shock wave lithotripsy) or to a feature unique to calcium phosphate stones. We determined whether calcium phosphate stone composition affects the stone-free rate of percutaneous nephrolithotomy.
Materials and Methods: Percutaneous nephrolithotomy was performed
in 111 patients between 2001 and 2006 and stone fragments were analyzed for calcium phosphate composition. Patients were categorized into
groups based on calcium phosphate content. All patients underwent preoperative computerized tomography. Patients were considered stone-free after percutaneous nephrolithotomy when fragments were 2 mm or less on noncontrast computerized tomography.
Results: A total of 213 percutaneous nephrolithotomies were performed. An increased percent of calcium phosphate was related to a decreased percutaneous nephrolithotomy success rate (p = 0.005), independent of preoperative stone burden (p = 0.8). Patients with greater than 60% calcium phosphate stones were significantly Cell Penetrating Peptide less likely to. be stone-free after percutaneous nephrolithotomy than those with less calcium phosphate (60%, OR 2.45, 95% Cl 1.103-5.4401 vs 80%, OR 3.72, 95% CI 1.33-10.44).
Conclusions: High calcium phosphate renal stone content leads to a decreased stone-free rate. Further study is required to determine the mechanism of stone resilience as well as the most appropriate treatment modality in patients with high calcium phosphate composition kidney stones.”
“Purpose: We determined the differences in outcome between ureteral stenting and nonstenting following uncomplicated ureteroscopy for distal ureteral stones.