PubMed 25. Ge Y, Old I, Saint Girons I, Charon N: Molecular characterization of a large Borrelia burgdorferi motility operon which is initiated by a consensus Torin 1 mw σ 70 promoter. J Bacteriol 1997,179(7):2289–2299.PubMed 26. Nichols TL, Whitehouse CA, Austin FE: Transcriptional analysis of a superoxide dismutase gene of Borrelia burgdorferi. FEMS Microbiol Lett 2000,183(1):37–42.CrossRefPubMed 27. Riley SP, Bykowski T, Babb K, von Lackum K, Stevenson B: Genetic and physiological characterization of the Borrelia burgdorferi ORF BB0374- pfs – metK – luxS operon. Microbiology 2007,153(7):2304–2311.CrossRefPubMed

28. Studholme DJ, Buck M: The biology of enhancer-dependent transcriptional regulation in bacteria: insights from genome sequences. FEMS Microbiol Lett 2000,186(1):1–9.CrossRefPubMed 29. Caimano MJ, Eggers CH, Gonzalez CA, Radolf JD: Alternate sigma factor RpoS is required for the in vivo -specific

repression of Borrelia burgdorferi plasmid lp54-borne ospA and Tozasertib clinical trial lp6.6 Genes. J Bacteriol 2005,187(22):7845–7852.CrossRefPubMed 30. Probert WS, Johnson BJ: Identification of a 47 kDa fibronectin-binding protein expressed by Borrelia burgdorferi isolate B31. Mol Microbiol 1998,30(5):1003–1015.CrossRefPubMed 31. Parveen N, Robbins D, Leong JM: Strain variation in glycosaminoglycan recognition influences cell-type-specific binding by Lyme disease spirochetes. Infect Immun 1999,67(4):1743–1749.PubMed 32. Guo BP, Norris SJ, Rosenberg LC, Hook M: Adherence of Borrelia burgdorferi to the proteoglycan decorin. Infect Immun 1995,63(9):3467–3472.PubMed 33. King SJ, Hippe KR, Weiser JN: Deglycosylation of human glycoconjugates by the sequential activities of exoglycosidases expressed by Streptococcus pneumoniae. Mol Microbiol 2006,59(3):961–974.CrossRefPubMed 34. Medzihradszky KF: Characterization of protein N-glycosylation. Methods Enzymol 2005,

405:116–138.CrossRefPubMed 35. Yang XF, Hubner A, Popova TG, Hagman KE, Norgard MV: Regulation STK38 of expression of the paralogous Mlp family in Borrelia burgdorferi. Infect Immun 2003,71(9):5012–5020.CrossRefPubMed 36. Lybecker MC, Samuels DS: Temperature-induced regulation of RpoS by a small RNA in Borrelia burgdorferi. Mol Microbiol 2007,64(4):1075–1089.CrossRefPubMed 37. Eggers CHCM, Radolf JD: Sigma factor selectivity in Borrelia burgdorferi : RpoS recognition of the ospE/ospF/elp promoters is dependent on the sequence of the -10 region. Mol Microbiol 2006,59(6):1859–1875.CrossRefPubMed 38. Elias AF, Bono JL, phosphatase inhibitor Carroll JA, Stewart P, Tilly K, Rosa P: Altered stationary-phase response in a Borrelia burgdorferi rpoS mutant. J Bacteriol 2000,182(10):2909–2918.CrossRefPubMed 39. Samuels DS, Mach KE, Garon CF: Genetic transformation of the Lyme disease agent Borrelia burgdorferi with coumarin-resistant gyrB. J Bacteriol 1994,176(19):6045–6049.PubMed 40. Hanahan D: Studies on transformation of Escherichia coli with plasmids. J Mol Biol 1983, 166:557–580.