HIPPOKRATIA 2019, 23(2) 92-94. Copyright 2019, Hippokratio General Hospital of Thessaloniki.BACKGROUND Management of coronary artery graft failure, specially in the web site of a recent distal anastomosis, is a challenging medical circumstance, and literary works data are scarce. CASE SERIES We present an instance group of clients with coronary artery bypass graft failure as much as 6 months after medical revascularization, who had been treated with percutaneous coronary input in the website of distal graft anastomosis through the graft or the indigenous vessel. CONCLUSIONS Percutaneous coronary intervention at distal graft anastomotic lesions is challenging, it can be performed from often the graft or the indigenous vessel, additionally the angiographic result might not often be optimal. HIPPOKRATIA 2019, 23(2) 87-91. Copyright 2019, Hippokratio General Hospital of Thessaloniki.AIM Atherosclerosis of the big arteries associated with neck could possibly be related to the cognitive and motor shortage. We investigated if the atherosclerosis of common carotid and femoral arteries in customers with multiple sclerosis (MS) is straight linked with a disability and has an inverse relationship with intellectual performance. TECHNIQUES We enrolled, in this potential research, a random test of 105 patients with MS and 22 healthier controls. All individuals received an extensive neuropsychological assessment. The real disability ended up being quantified aided by the Expanded Disability reputation Scale (EDSS). We used ultrasound for the carotid and femoral arteries to guage the degree of stenosis and intima-media depth (IMT). We produced a novice ultrasound list of atherosclerosis (ATHUS rating) in line with the arterial stenosis together with IMT associated with the carotid and femoral arteries. We then compared the outcome associated with the psychometric evaluation and EDSS because of the ATHUS score. OUTCOMES The analysis demonstrated that greater intellectual function is correlated with reduced values of ATHUS score (p =0.01). Additionally, there was clearly a primary correlation between the ATHUS rating and EDSS (p =0.001). SUMMARY Our results claim that the amount of atherosclerosis, as computed because of the ATHUS score, is directly linked to reasonable intellectual score and higher sensory and motor impairment. HIPPOKRATIA 2019, 23(2) 81-86. Copyright 2019, Hippokratio General Hospital of Thessaloniki.BACKGROUND Cutaneous diseases are observed with increasing length and seriousness of renal disease in patients with persistent kidney infection (CKD). This study aimed to elucidate dermatological manifestations at different stages of CKD and determine their relationship with interleukin 31 (IL-31), a T-cell cytokine that induces severe pruritus, and uridine diphosphate (UDP)-glucose ceramide glucosyltransferase (UGCG), an enzyme that metabolizes ceramide, which plays an important role in moisturizing epidermis. METHODS In this retrospective cohort study 145 customers with a mean age 46 ± 17 years were categorized into hemodialysis (group 1), peritoneal dialysis (group 2),  kidney Immuno-chromatographic test transplant (group 3), CKD (group 4), and healthy control (group 5) teams. Serum IL-31 and  UGCG levels had been Selleckchem Epertinib calculated making use of enzyme-linked immunosorbent assay, and medical skin experts examined dermatological manifestations. Leads to the entire cohort, pruritus ended up being significantly and inversely correlated with glomerular purification rate and serum hemoglobin and albumin levels (p less then 0.005). Also, pruritus ended up being far more frequent in-group 2 than in team 5; and notably less regular in group 3 compared to teams 1, 2, and 4 (p =0.01). In-group 4, the patients with longitudinal nail ridges had significantly greater serum IL-31 amounts compared to those without longitudinal nail ridges within their medullary rim sign nails (p =0.02). Moreover, in-group 2, the clients with pruritus had significantly reduced UGCG amounts than those without pruritus (p =0.045). CONCLUSION IL-31 might may play a role when you look at the growth of longitudinal nail ridges, whereas UGCG might provide protection from pruritus and xerosis in clients with CKD.  HIPPOKRATIA 2019, 23(2) 75-80. Copyright 2019, Hippokratio General Hospital of Thessaloniki.BACKGROUND Although cardiopulmonary workout (CPX) test is an essential device when it comes to evaluation of useful ability in professional athletes, restricted information exists in connection with cardiorespiratory performance in youthful elite volleyball players. The primary objective associated with the current study would be to determine the maximal oxygen uptake (VO2max) and ventilatory anaerobic threshold (VT) during the CPX test in young male and female volleyball people. Furthermore, to spell it out the behavior associated with novel cardiorespiratory optimal point (COP) index also to examine its organization with VO2max and VT. TECHNIQUES Eleven adolescent male (15.18 ± 0.75 years of age) and 13 feminine (14.77 ± 0.44 years old) volleyball players underwent a graded maximal exercise test on a treadmill until fatigue so that you can obtain VO2max, VT and COP. The COP ended up being set since the cheapest ventilation (VE)/VO2 proportion at a given min of spiroergometry. RESULTS COP values would not differ notably between the two sexes (19.81 ± 1.29 and 20.44 ± 2.63 in women and men, correspondingly) and it also was accomplished at a speed of 3.41 ± 0.89 km/hr in males, and 3.78 ± 0.76 km/hr in females, lower than that achieved in the VT. COP wasn’t correlated with VO2max (56.32 ± 6.36 ml/kg/min and 44.78 ± 3.65 ml/kg/min) nor with VT (34.81 ± 10.13 ml/kg/min and 34.13 ± 5.87 ml/kg/min) in male and feminine youthful volleyball people, correspondingly. CONCLUSIONS The novel submaximal cardiorespiratory list of COP does not appear to be linked to the conventional aerobic capacity indices in professional athletes such as for instance VO2max and VT. Thus, it probably constitutes a separate parameter that needs to be additional assessed regarding its significance in both clinical analysis and recreations performance assessment of professional athletes.