The PCPs only ordered an antibiotic for travelers’ diarrhea for half of the patients who were indicated and less of their patients picked it from the pharmacy compared to the pharmacists. Since the PTC visits are consistently structured to include extensive counseling on food/water precautions and food/water-borne illnesses, this may help explain why higher antibiotic pickup rates occurred among the PTC group.

In both groups, pickup rates for antibiotics were lower than for antimalarials, suggesting that the study population may perceive food- and water-borne illnesses GSK126 as less serious than malaria. Omission of recommendations for antimalarials and vaccines when indicated was also common among PCPs. Purpose of travel and activities planned were only documented in half of the PCP visits, suggesting that the providers either do not take these variables into consideration or simply do not routinely

document these patient-specific factors. Practice guidelines suggest that taking into account these itinerary variables impacts the assessment of each patient’s indication for medications and vaccines, Trichostatin A and thus this may have affected the recommendations of PCPs.9 The use of medications for travel to destinations where antimicrobial resistance exists, such as ciprofloxacin as self-treatment for travelers’ diarrhea in Thailand or chloroquine for malaria chemoprophylaxis in Africa was another area where the PTC consistently showed higher compliance with national/international travel guidelines. Other areas of inconsistency between PCPs and the PTC involved recommendations of vaccines for diseases where no risk exists, such as Yellow Fever vaccine for a traveler to Southeast Asia. The observations that the PTC saw more travelers with volunteer work as their primary purpose and the PCPs saw more travelers with school as their primary purpose

was expected. The PTC frequently conducts group consultations, which can be more convenient for large, organized volunteer groups. Many Pyruvate dehydrogenase lipoamide kinase isozyme 1 study abroad programs require a medical exam and clearance prior to a student enrolling, which would necessitate a traveler to have a visit with a PCP. Since visits with the PTC and PCP were equal in length, vaccines were administered in the same clinic, and medications were dispensed from the same pharmacy, these factors should not have influenced outcomes. The PCPs generally had family medicine or internal medicine training background and did receive a 1-hour travel medicine update every year as part of a health center grand rounds program. While previous studies of international community pharmacists have not been positive toward their travel medicine knowledge, no such study has been conducted in the United States, where all schools of pharmacy confer only the Doctor of Pharmacy degree after 6 to 8 years of training and many graduates pursue post-graduate residencies.