This study investigated the effect of raised body mass index (BMI, calculated as kg/m(2)) on the rate of CKD progression in a group of patients with CKD and type 2 diabetes mellitus.
Methods: The Chronic Renal Insufficiency Standards Implementation Study (CRISIS) is a large epidemiological study conducted in Manchester, UK. From the CRISIS database, we assessed the rate of progression of CKD in 229 adults who met the inclusion criteria.
Baseline measurements such as BMI, estimated glomerular filtration rate (eGFR) and systolic and diastolic blood pressure were collected. eGFR measurements were obtained during follow-up to calculate the rate of eGFR change (Delta eGFR). Linear regression analysis and independent sample t-test were used in
data analysis.
Results: After a mean follow-up period of 31 months, linear regression see more analysis showed no relationship between Delta eGFR and BMI. Furthermore, independent sample t-test comparing the obese (BMI >= 30) and nonobese (BMI <30) groups’ Delta eGFR showed no statistical significance this website (p=0.572). Similar results were observed after stratification according to CKD stages 3, 4 and 5.
Conclusion: Raised BMI did not influence the rate of progression of chronic kidney disease in patients with type 2 diabetes mellitus.”
“Objective: To evaluate a psycho-educational program (PeP) for parents of children with cancer (PoCwC) in Malaysia.
Methods: Seventy-nine parents were invited to be either in an intervention (n = 41) or a control group (n = 38). Baseline assessment took place upon agreement of participation. Shortterm effects were measured four weeks after the intervention. Control parents received standard care. Intervention parents received, in addition to standard care, 4 x 50 min sessions of information on childhood cancer and coping strategies.
Results: Repeated measures of ANOVAs revealed increased
Alisertib in vitro knowledge about cancer (p = 0.01) in the intervention parents compared with standard care. Intervention parents reported reduced anxiety and increased activities with children after the program; however, differences were not significant.
Conclusions: This PeP, the first of its kind in Malaysia, has significantly increased levels of knowledge among parents of seriously ill children which may point towards the potential for these services to increase coping in Malaysian PoCwC. Copyright (C) 2009 John Wiley & Sons, Ltd.”
“Background: The prolongation of steroid therapy for an initial episode of idiopathic nephrotic syndrome may decrease any relapses. Two treatment protocols were compared with the objective of finding the frequency of relapses and side effects of steroid in the following 12-month period.
Methods: A hospital-based prospective study was conducted of 80 children allocated randomly to receive prolonged (5-month) or standard (3-month) prednisolone therapy.