Tumor necrosis factor-alpha-stimulated gene-6 expression was suppressed in the OPLL continuous and segmental groups. ALP expression as well as ALP activity staining was higher in the OPLL continuous group than in the OPLL segmental group.
Conclusion. The study revealed genetic differences in the osteogenic differentiation
potency between the OPLL continuous and segmental groups. We propose to distinguish OPLL continuous group from segmental group in biochemical studies on OPLL.”
“Biological modeling of wastewater processes has gained importance for their design, control and operation. However, this requires consistent information on the biological activity. Microcalorimetry has also been developed to investigate biological processes and measure bacterial metabolisms. This measurement is done on the basis of the heat (produced or consumed) and therefore has NVP-HSP990 a wider range of applicability compared to other methods based on the chemical analyses of substrate consumption or product formation. For this purpose, a 2 L Bio-RC1 (Mettler-Toledo) has been modified to reach a resolution of 5-10 mW L(-1) and applied to research projects on activated sludge characterization. Several calorimetric applications are presented regarding studies of biomass activity (useful to achieve kinetic and stoichiometric coefficients) and pollutants degradation in aerobic, anoxic and anaerobic conditions. HTS assay (C) 2010 Elsevier B.V.
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“Study Design. A cross sectional multicenter 5-Fluoracil inhibitor study in six outpatient Rehabilitation Centers (RCs) in the Netherlands.
Objective. This study aims to confirm or refute the finding that a strong
relationship exists between psychosocial distress and self-reported disability in patients with nonspecific chronic low back pain (CLBP) by analyzing this relationship in patients with CLBP admitted for treatment in six RCs.
Summary of Background Data. A strong relationship between psychosocial distress and self-reported disability in patients with CLBP is suggested. However, in former research weak relationships were found in two of the RCs participating in this study.
Methods. Total study sample consisted of 293 patients (30-66 per RC) with CLBP, admitted for outpatient multidisciplinary rehabilitation in one of the six participating RCs. Psychosocial distress was measured with the Symptom Checklist-90-Revised (SCL-90-R), self-reported disability with the Roland Morris Disability Questionnaire (RMDQ). Pearson correlation coefficients between psychosocial distress and self-reported disability were calculated. Multivariate regression analysis was performed to analyze the relationship between SCL-90-R and VAS pain (independent variables) and RMDQ (dependent variable) for the total group and for each RC separately. A multivariate regression analysis was performed to analyze the relationship between all baseline characteristics and RMDQ in the total group.
Results.