21 The study showed

that the incidence of PONV ranged from 12% to 35%. The study shows that patients who experienced PONV might have received higher doses of opioids. In an earlier study on volunteers, a high incidence of nausea was observed.11 and persisted for hours in some of the subjects. However, some of the subjects in that study,11 received much higher doses of remifentanil than that used in the present study. Also, In our study, there was no significant difference between the three groups in terms of pain score at all the Inhibitors,research,lifescience,medical times. The mean VAS for pain and meperidine consumption in group R was insignificantly more than that in group F at recovery and 4 hour after surgery. Similar to our findings, an earlier study found that compared to remifentanil, fentayl used for balanced anesthesia could produce a better early postoperative analgesia.3 The differential effects of remifentanil may be Inhibitors,research,lifescience,medical due to its short half-life, which influences the time course of pain Caspase activation relief compared Inhibitors,research,lifescience,medical to longer acting opioids.1 The findings of the present study should be

considered in light of two limitations. One limitation is that the effect of opioids on clinical outcome variables such as time to discharge or number of unexpected hospital readmissions could not be addressed, because all patients remained in the hospital for 24 hours after discharge from the recovery Inhibitors,research,lifescience,medical area. The second limitation is the lack of both strict follows up methodology and proper statistical power and small sample size. Therefore, further studies with different methodologies and appropriate sample size might be required to evaluate PONV and pain. Conclusion The Inhibitors,research,lifescience,medical findings of the

present study may suggest that compared with fentanyl, remifentanil had no effect on PONV and postoperative pain relief. They also show that early postoperative analgesia was better with fentanyl, and postoperative meperidine consumption was significantly less with fentanyl than with remifentanil or combined fentayl and morphine. Conflict of Interest: None declared
Coagulase-negative staphylococci (CoNS) are the major causes of hospital acquired infections, and are often isolated from neonates, immunocompromised individuals and patients with indwelling prosthetic devices.1,2 Among Terminal deoxynucleotidyl transferase the CoNS, Staphylococcus epidermidis is frequently associated with bacteremia, urinary tract infections and infections associated with indwelling medical devices.3 The major concern with regard to the treatment of staphylococcal infections is antibiotic resistance among the clinical isolates. Indeed, over 90% of all nosocomial isolates are resistant to penicillin and an increasing number are becoming resistant to the semisynthetic, β-lactamase resistant derivatives represented by oxacillin.