Sleep/wake seizure distribution predicted tonic-clonic evolution better than time of day, with more occurring during sleep (p < 0.001). Tonic-clonic evolution occurred most frequently between 12-3 AM and 6-9 AM (p < 0.05). Patients with generalized EEG onset had more tonic-clonic evolution between 9 AM and 12 PM (p < 0.05). Patients with extratemporal focal seizures were more likely to evolve during sleep (p < 0.001); this pattern was not found in patients with temporal or generalized Torin 1 ic50 seizure onset on EEG. Patients without MRI lesions were more likely to evolve between 12 AM and 3 AM (p <

0.05), in the sleeping state (p < 0.001), and at night (p < 0.05). Logistic regression revealed that sleep and older patient age were the most important predictors of GTC evolution.\n\nConclusion: GTC evolution occurs most frequently out of sleep and in older patients. Our results may assist in seizure prediction, individualized treatment patterns, and potentially complication and SUDEP prevention. (c) 2012 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.”
“Highly oriented M-type barium ferrite

(BaM) thin films Gamma-secretase inhibitor were deposited by sputtering on Pt-coated Si Substrate with different substrate temperatures. X-ray diffraction and atomic force microscopy results show that BaM films have crystal texture of c-axis grains perpendicular to film plane with apparent hexagonal morphology. On the other hand, it is clearly observed that the remanent magnetization (Mr) in out-plane is higher than those in in-plane, and the Mr in out-plane increases with increasing the substrate temperature, reaching maximum when Proteases inhibitor substrate temperature (Ts) is 600 degrees C. The hysteresis curves also indicate that the BaM thin film exhibits nice self-biased property with 4 pi Mr of 3803.04 Gs, squareness ratio (Mr/Ms) of 0.96, and coercivity of 1767.3 Oe. These results make sure that these BaM films have potential for use in self-biasing microwave/millimeter wave magnetic devices such as circulators and isolators. (C) 2013 American Institute of Physics.”
“The formulation

of gluten-free bread, which will be suitable for patients with coeliac disease, was optimized to provide bread similar to French bread. The effects of the presence of hydrocolloids and the substitution of the flour basis by flour or proteins from different sources were studied. The added ingredients were (1) hydrocolloids (carboxymethylcellulose [CMC], guar gum, hydroxypropylmethylcellulose [ HPMC], and xanthan gum), and (2) substitutes (buckwheat flour, whole egg powder, and whey proteins). The bread quality parameters measured were specific volume, dry matter of bread, crust color, crumb hardness, and gas cell size distribution. Specific volume was increased by guar gum and HPMC. Breads with guar gum had color characteristics similar to French bread. Hardness decreased with the addition of hydrocolloids, especially HPMC and guar.