The hepatic TG and TC concentrations of persimmon-vinegar administered groups were significantly lower compared with the HD group. Liver acid insoluble acylcarnitine (AIAC) was significantly higher in the HD-PV2 than in HD and HD-V groups.

The acetyl-CoA carboxylase (ACC) mRNA level tended to lower in all the vinegar administered groups compared with the HD group. These results suggest that the persimmon-vinegar has anti-obesity properties.”
“Fluoroquinolone (FQ)-associated tendinopathy and myopathy are uncommon but well recognized complications of the use of this class of antibacterial agents. The case of a 63-year-old previously asymptomatic female patient who developed severe left shoulder tendinopathy after surreptitiously doubling the prescribed dose of levofloxacin for the treatment of community-acquired ZD1839 purchase pneumonia is reported here. Surgical stabilization with suture anchors and subacromial decompression were needed. (C) 2012 Elsevier Editora Ltda. All rights reserved.”
“As the global market expands, it is critical that researchers understand how cultural factors influence the expectations and liking for a food product. The objectives of this study were CBL0137 mouse to identify the optimal sweetness level for a sports-drink for consumers originating

from different countries and to investigate the factors affecting the optimal sweetness level. In the first study, respondents (n=372) originated from 5 Asian countries and US tasted and evaluated the sports-drink at 4 sweetener levels. Consumers (n=256) from 3 Asian countries and US participated in the second study. Consumers evaluated the concept and sensory expectations for the ‘lemon-lime flavored’ sports-drink and other beverages. The optimal sweetness level for the sports-drink was lower for Americans than Asians. The familiarity to the product was a key factor affecting the optimal sweetener level. The results also suggested that information can differently influence the product acceptance depending on one’s familiarity

with the product.”
“E >-Poly-l-lysine (E >-PLL) produced by Streptomyces albulus CGMCC 1986 was fractionated using ultra-filtration technique with 2 and 5 kDa cut-offs of membrane. The number-average molecular weight of each fraction was 3-MA order determined by (1)H nuclear magnetic resonance (NMR) method. The number-average molecular weights of the cutoffs of 5 and 2 kDa and the filtrate are 4,230.95, 3,687.80, and 1,900.82 Da, respectively. (1)H NMR indicates the chemical shifts of alpha-H, beta-H, gamma-H, delta-H, and E >-H are very similar to all the fractions. Fourier transform-infrared (FTIR) spectra showed that the E >-PLL solid samples obtained by freeze-drying at pH 5 with molecular weights higher than 2 kDa take on a beta-turn conformation, however, the fraction with molecular weight smaller than 2 kDa adopts random coil structure.

17, 0.64), whereas no association was shown with the executive functioning factor. Removing specific components from the PNNS-GS did not modify the findings.

Conclusion: This study suggests that strong compliance with nutritional recommendations in midlife is associated in elderly individuals with better verbal memory, which is a cognitive domain that is particularly vulnerable to pathologic aging

and Alzheimer disease. This trial was registered at clinicaltrials.gov as NCT00272428. Am J Clin Nutr 2011;93:200-10.”
“The pasteurization process of litchi causes thermal texture degradation. In order to optimize the process condition, the thermal firmness degradation kinetics of litchi was studied. Linear regression of first order kinetics-Arrhenius https://www.selleckchem.com/products/17-AAG(Geldanamycin).html equation and non-linear regression of Weibull-Log logistic model (WeLL) were employed. Fractional conversion technique was also used to examine its effect on improving the accuracy of models. The results indicated that in three thermal treatments Compound C at 80, 85 and 90 C. the thermal firmness degradation curve of litchi showed a short term shoulder-like increase at the initial heating stage, followed by a decrease and remained a tail-like non-zero equilibrium stage during prolonged heating. WeLL model displayed better accuracy for litchi texture modeling than first order-Arrhenius equation. Fractional conversion technique was effective in increasing the

accuracy of first order kinetics comparable to those of Weibull model. It is concluded that WeLL model can be applied in modeling thermal food texture degradation. (C) 2010 Elsevier Ltd. All rights reserved.”
“Patients on hemodialysis (HD) are prone to atherosclerotic cardiovascular complications. In an attempt to determine the significance GW4869 supplier of several atherosclerotic and thrombogenic parameters as risk factors for atherothrombotic cardiovascular disease (CVD) in these patients, we compared two groups of non-diabetic HD patients matched for age and sex, selected according to the absence (group 1, n = 30) or presence (group 2, n = 30) of symptomatic atherothrombotic vascular disease affecting the coronary, cerebral, or peripheral arteries. Duration of HD, primary renal disease (PRD),

presence of hypertension, EPO treatment, and smoking habits were recorded. Serum total cholesterol (TC), triglycerides (TG), HDL-C, LDL-C, TC/HDL-C ratio, lipoprotein(a) (Lp(a)), fibrinogen (FG), plasminogen (PLG), fibronectin (FN), and hematocrit (HCT) were measured pre-HD in a midweek session. The same blood parameters were also assessed in twenty matched clinically healthy subjects (controls). None of the blood parameters differed between groups 1 and 2, except for serum Lp(a) and FN, which were higher in group 2 (p = 0.005 and p = 0.041, respectively). Both groups were not different regarding PRD, duration of HD, and EPO treatment, but the presence of hypertension and smoking habits were more common in group 2 (p = 0.008 and p = 0.045, respectively).

The scission products further decomposed into lower molecular weight products with drip, which caused the combustion under specimens. There were no big differences in a weight loss temperature and scission products at high temperature between a low

molecular weight of polyethylene and a high molecular weight of polyethylene. selleckchem Therefore, the degradation and combustion behavior of scission products of polyethylene in primary degradation warrant further research on flame retardant of polyethylene. (c) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 122: 436-443, 2011″
“Structural, transport, and magnetoelectric (ME) properties of delafossite oxides CuCr1-xO2 with 0 <= x <= 0.10 were extensively investigated. The Rietveld refinement shows that the Cu-O bond length decreases with increasing Cr deficiency, indicative of the presence of a mixed valence state of Cu+/Cu2+ and an enhancement of the hybridization between Cu 3d and O 2p orbitals. As a result, it leads to a decrease of room-temperature https://www.selleckchem.com/products/cbl0137-cbl-0137.html resistivity by two orders of magnitude. The deduced effective moment for the Cr-deficient samples is larger than the one only taking into account the contribution from Cr3+ with S = 3/2. This demonstrates that Cu2+ is present in the

Cr-deficient samples, giving rise to excess holes at the Cu site. Below T-N(Cr) similar to 24 K, the magnetocapacitance [epsilon(H)-epsilon(0)]/epsilon(0) exhibits a distinct field dependence and deviates from the square of magnetization M-2. These findings suggest that the ME coupling in CuCr1-xO2 with higher x is modulated by an increase of the spin fluctuations in the Stem Cells & Wnt inhibitor CrO2 triangular lattice through the interplay

between charge and spin degrees of freedom. (C) 2011 American Institute of Physics. [doi:10.1063/1.3544498]“
“Medullary thyroid carcinoma (MTC) accounts for 5-8% of all thyroid cancers. MTC is mainly sporadic in nature, but an hereditary pattern [multiple endocrine neoplasia type 2 (MEN 2)] is present in 20-30% of cases, transmitted as an autosomal-dominant trait due to germline mutations of the RET proto-oncogene. About 98% of patients with MEN 2 have germline mutations in exons 5, 8, 10, 11, 13, 14, 15 or 16 of the RET gene. The primary treatment of both hereditary and sporadic forms of MTC is total thyroidectomy and removal of all neoplastic tissue present in the neck. The therapeutic option for lymph node surgery should be dictated by the results of presurgical evaluation. After total thyroidectomy, measurements of serum calcitonin (CT) and carcinoembryonic antigen are of paramount importance in the postsurgical follow-up of patients with MTC as they reflect the presence of persistent or recurrent disease. Complete remission is demonstrated by undetectable and stimulated serum CT measurement.

No treatment effect on postweaning performance and on blood concentrations of folic acid and vitamin B(12) was observed. In the ileum, the percentage of CD4(-)CD8(+low) T cells was greater (P = 0.05) in 18-d-old nursed piglets treated with PA than in those of the CTRL and PA+SCB groups. In the MLN, the percentage AZD3965 inhibitor of CD8(+) T cells was not affected by any of the treatments at d 18 and 24 but decreased (P = 0.006) after weaning. In the blood,

CD8(+) T cells were not affected by treatments or weaning. After the ETEC challenge (d 52), bacterial translocation to MLN was reduced (P = 0.05) in pigs treated with PA, SCB, PA+SCB, or ABT compared with CTRL. No treatment effect was observed on blood leukocyte populations after ETEC challenge, although a time effect (d 42 vs. 52) indicated that blood CD4(+) and gamma delta-T lymphocytes were increased (P < 0.05) on d 52 compared with d 42, whereas CD4(-)CD8(+low) T lymphocytes and monocytes were markedly reduced (P < 0.01). Finally, the IgA concentration in ileal flushes collected on d 42 and 52 was greater in SCB and CTRL piglets than in ABT and PA piglets. In conclusion, probiotics may have the potential to modulate click here establishment of lymphocyte populations

and IgA secretion in the gut and to reduce bacterial translocation to MLN after ETEC infection.”
“An area of increasing concern and scientific scrutiny is the potential contamination of drug products by leachables entering the product during manufacturing and storage. These contaminants may either have a direct safety impact

on the patients or act indirectly through the alteration of the physicochemical properties of the product. In the case of biotherapeutics, trace BIIB057 cost amounts of metal contaminants can arise from various sources, but mainly from contact with stainless steel (ss). The effect of the various factors, buffer species, solution fill volume per unit contact surface area, metal chelators, and pH, on metal leachables from contact with ss over time were investigated individually. Three major metal leachables, iron, chromium, and nickel, were monitored by inductively coupled plasma-mass spectrometry because they are the major components of 316L ss. Iron was primarily used to evaluate the effect of each factor since it is the most abundant. It was observed that each studied factor exhibited its own effect on metal leachables from contact with ss. The effect of buffer species and pH exhibited temperature dependence over the studied temperature range. The metal leachables decreased with the increased fill volume (mL) per unit contact ss surface area (cm(2)) but a plateau was achieved at approximately 3 mL/cm(2). Metal chelators produced the strongest effect in facilitating metal leaching.

The cutaneous lesions disappeared after a 3-month treatment with the tumour necrosis factor-alpha (TNF-alpha) inhibitor etanercept. QNZ Anti-TNF-alpha agents can antagonise the multiple effects of TNF-alpha on the immune system, effects that are required for the continued maintenance of granulomatous structure, and offer

a therapeutic strategy in the treatment of IGD associated with arthritis.”
“There are few pediatric data regarding manifestations and outcomes of Rathke’s cleft cysts (RCC). We retrospectively reviewed 13 cases treated at Massachusetts General Hospital over 10 years. Age at presentation was 12-17 years, except for one 7-year-old who presented with sexual precocity. There was a female preponderance [11 see more females, 2 males, p=0.01], and all were pubertal at diagnosis. Common features at presentation were headaches (11/13), endocrine abnormalities (5/13) and visual disturbances (2/13). Four patients underwent transsphenoidal surgery. Symptoms improved in all but one, in whom headaches persisted. Recurrent growth in one patient was treated successfully by excision. For conservatively treated patients, cyst size was unchanged over follow-up (6 months-5 years). Female preponderance and pubertal presentation suggest a possible link between sex hormones and RCC pathogenesis. Although estrogen and progesterone receptor immunostaining was negative in the cyst lining,

estrogen receptor immunostaining was positive in adjacent pituitary cells. Further investigations regarding this issue are warranted.”
“The formation of Fe3O4 nanoparticles by hydrothermal process has been studied. X-ray Diffraction measurements were carried out to distinguish between the phases formed during the synthesis. Using the synthesized Fe3O4 nanoparticles,

poly(vinyledene fluoride)-Fe3O4 composite films were prepared by spin coating method. Scanning electron microscopy of the composite films showed the presence of Fe3O4 nanoparticles in the form of aggregates on the surface and inside of the porous polymer matrix. Differential Scanning calorimetry revealed that the crystallinity of PVDF decreased with the addition of Fe3O4. The conductitivity of the composite films was strongly influenced Staurosporine chemical structure by the Fe3O4 content; conductivity increased with increase in Fe3O4 content. Vibration sample magnetometry results revealed the ferromagnetic behavior of the synthesized iron oxide nanoparticles with a Ms value of 74.50 emu/g. Also the presence of Fe3O4 nanoparticles rendered the composite films magnetic. (C) 2010 Wiley Periodicals, Inc. J Appl Polym Sci 119: 968-972, 2011″
“When an adult suffers from muscular symptoms, the diagnosis of polymyositis is often accepted if muscular biopsy reveals necrosis, fibrosis and cellular infiltrate with high expression of major histocompatibility complex class I. Late-onset limb-girdle muscular dystrophy (LGMD) can also be considered.

Using a 5-mm cutoff (two

studies), sensitivity varied between 40% and 84%, and specificity 78-89%.

There is lack of data to reliably selleck inhibitor estimate accuracy of BWT in DO.”
“The potential role of domestic dogs in the long-distance transmission of bluetongue virus (BTV) is currently unproven. This study set out, through an experimental infection study, to investigate whether domestic dogs mount a viraemia post-infection with a field strain of BTV serotype 1. All six experimentally infected dogs seroconverted within 14 days and viral RNA was detected in the blood of the dogs, albeit at significantly lower levels than that seen in domestic ruminants. There was no clear evidence for viral replication in the dogs as no increase in viral RNA was

observed in, and it was not possible isolate virus from, the blood of the dogs. There was however evidence for learn more a persistence of viral RNA in the blood of the dogs, which may be evidence for a low level of replication or could be indicative of persistence of the viral inoculum. (C) 2013 Elsevier Ltd. All rights reserved.”
“We argue that impulsiveness is characterized by compromised timing functions such as premature motor timing, decreased tolerance to delays, poor temporal foresight and steeper temporal discounting. A model illustration for the association between impulsiveness and timing deficits is the impulsiveness disorder of attention-deficit hyperactivity disorder (ADHD). Children with ADHD have deficits in timing processes of several temporal domains and the neural substrates of these compromised timing functions are strikingly similar to the neuropathology of ADHD. We review our published and present novel functional magnetic resonance imaging data to demonstrate that ADHD children show dysfunctions in key timing regions of prefrontal, cingulate, striatal and cerebellar location during temporal processes of several time buy Apoptosis Compound Library domains including time discrimination of milliseconds, motor timing to seconds and temporal discounting of longer time intervals. Given that impulsiveness, timing

abnormalities and more specifically ADHD have been related to dopamine dysregulation, we tested for and demonstrated a normalization effect of all brain dysfunctions in ADHD children during time discrimination with the dopamine agonist and treatment of choice, methylphenidate. This review together with the new empirical findings demonstrates that neurocognitive dysfunctions in temporal processes are crucial to the impulsiveness disorder of ADHD and provides first evidence for normalization with a dopamine reuptake inhibitor.”
“J Granton. Outcomes in pulmonary hypertension: Beyond 40 metres. Can J Cardiol 2010;26(Suppl B):12B-16B.

Advances in treatment options have improved the quality of life and exercise capacity of patients with pulmonary hypertension. Newer oral therapies have postponed the requirement for more obtrusive parenteral therapies and transplantation.

Good Manufacturing Practice (GMP) for biodrugs has been developed in certain regions such as the EU, US, and Japan. Due to differences in manufacturing methods and systems, product-specific GMP guidelines are evolving. In general, there are variations in GMP guidelines between countries, which lead to difficulty for the manufacturers in conforming to different standards, thus entailing delays in the commercialization of biodrugs. There is a need to develop a unified regulatory guideline for biodrug manufacturing across

various countries, which would be helpful in the marketing of products and trade. This review deals with the comparative framework and analysis of GMP regulation of biodrugs.”
“Induced supraventricular tachycardia (SVT) during electrophysiology studies (EPS) can be associated with hemodynamic changes. Traditionally, invasive

arterial blood pressure YM155 order has been used for continuous monitoring of these changes. This prospective study evaluated the efficacy of near-infrared spectroscopy (NIRS) monitoring during SVT. The use of NIRS has expanded with evidence of its accuracy selleck chemical and benefit in detecting cerebral hypoperfusion. This study aimed first to determine the hemodynamic changes associated with electrophysiology testing for SVT and second to determine whether the hemodynamic changes are associated with similar changes in the cerebral saturation as determined by NIRS. The study enrolled 30 patients 5-20 years of age with a history of SVT who underwent an EPS. The demographic data included age, gender, weight, height, and type of SVT. Hemodynamic data (invasive blood pressure and heart rate), NIRS, bispectral index (BIS), end-tidal carbon dioxide, and pulse oximetry were collected before and during three episodes of induced SVT. The linear correlation coefficient (r) was measured to calculate the relationship of the changes in systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) to the changes in NIRS values during the SVT episodes. Data from 22 patients were collected. The induction of SVT was associated mainly with a change in SBP and a less prominent change in DBP and MAP from

baseline. The changes in hemodynamic status were associated with minimal changes in cerebral saturations, as evidenced Bcl-2 inhibitor by an average absolute change in NIRS of < 1 from baseline value. The changes in hemodynamics were correlated linearly with cerebral saturation. Changes in SBP, DBP, and MAP were correlated positively with changes in NIRS, as denoted by (r) values of 0.52, 0.57, and 0.67 respectively, and a P value less than 0.05 for all three association tests. Induction of SVT during electrophysiology testing is associated with hemodynamic changes, mainly in SBP. In this study, these hemodynamic changes resulted in a minimal decrease in cerebral perfusion, as evidenced by minimal changes in the cerebral saturation measured by NIRS (0.

25 mm (mild), 12.5 mm (moderate), 25 mm (severe), or 50 mm (very

severe). The control group underwent laminectomy only. SEP and BBB recordings were performed once before injury, and then weekly for up to 7 weeks.

Results. Graded levels of injury produced concomitant attenuations in hindlimb SEP amplitudes. Following injury, 25 and 50 mm groups together differed significantly from 12.5 and 6.25 mm groups (P < 0.01). From week 5, differences between 12.5 and 6.25 mm groups also became apparent (P < 0.01), which showed significant electrophysiological improvement. However, no significant differences were observed between DZNeP order 25 and 50 mm groups, which showed negligible electrophysiological recovery. Although comparable differences between different groups were also detected by BBB after injury (P < 0.001), BBB was less sensitive in detecting any improvement in 6.25 and 12.5 mm groups.

Conclusion. SEP amplitudes and BBB scores decrease corresponding to increase in injury severity, however, these show different temporal patterns of recovery. CX-6258 These results

demonstrate the utility of SEPs in conjunction with BBB, to monitor therapeutic interventions in SCI research.”
“Vulnerability of hydrogels against thermal circumstances may be substantially eliminated via incorporating nanoclay to prepare nanocomposite hydrogels. In this research, chitosan-intercalated montmorillonite CBL0137 (ChitoMMT) was used as a bionanoclay to yield novel nanocomposite hydrogels based on 2-acrylamido-2-methylpropanesulfonic acid. The bionanoclay is suitable especially for preparing biomaterials used in biomedical, food, and pharmaceutical applications, unlike conventional commercial nanoclays (alkyl ammonium-intercalated MMT) which are not appropriate for bio-applications due to toxicity of the

intercalant particularly where the clay content is high. Two different crosslinkers (i.e., methylene bisacrylamide, and polyethyleneglycol dimethacrylate) were employed to synthesize the nanocomposites. The variations in swelling, rheological and thermal properties of the hydrogels were essentially attributed to thermally induced crosslink cleavage/formation depending upon the crosslinker nature. The nanocomposites comprised superior thermal properties in comparison with the clay-free hydrogel counterpart. They can preserve substantially their swelling ability for longer heating periods. (c) 2010 Wiley Periodicals, Inc. J Appl Polym Sci 116: 2548-2556, 2010″
“Oncocytic meningioma is an uncommon variant of meningioma, with only 20 reported cases to date, that is histologically characterized by the presence of neoplastic cells with granular eosinophilic cytoplasm rich in mitochondria. We present the clinicopathological features of a case of oncocytic meningioma in a 49-year-old Chinese female, along with a literature review.

Five patients underwent unilateral treatment and nine underwent bilateral treatment; only one P5091 supplier foot was analyzed in each of the latter patients. Standardized clinical examinations and three-dimensional gait analysis with a special foot model (Heidelberg Foot Measurement Method) were performed before and at a mean of 28.8 months after surgery.

Results: The three-dimensional gait analysis revealed significant increases in tibiotalar and foot-tibia dorsiflexion during the swing phase after surgery. These increases were accompanied by a significant reduction in maximum

plantar flexion at the stance-swing transition but without a reduction in active range of motion. Passive ankle dorsiflexion measured in knee flexion and extension increased significantly without any relevant decrease in passive plantar flexion. The AOFAS (American Orthopaedic Foot & Ankle Society) score improved significantly.

Conclusions: Tibialis posterior tendon transfer was effective at correcting the foot drop component

of cavovarus foot deformity in patients with Charcot-Marie-Tooth disease, with the transfer apparently working as an active substitution. Although passive plantar flexion was not limited after surgery, active plantar flexion at push-off was significantly reduced and it is unknown whether SYN-117 manufacturer this reduction was the result of a tenodesis effect or calf WZB117 datasheet muscle weakness.”
“Objective: To determine if lipoprotein particle abnormalities correlate with arterial stiffness in children with type 1 diabetes (T1D).

Study Design: In this case-control study, we evaluated 70 children,

35 with T1D and 35 controls, ages 10-18 years, matched for age, sex, race, and BMI. Arterial stiffness was assessed by radial tonometry (AI(75)) and blood was collected for lipoprotein subclass analysis.

Results: T1D subjects had increased AI(75), decreased small LDL particle concentration (P=0.0067), increased large LDL particle concentration (P=0.007), increased large HDL particle concentration (P=0.0012), increased mean LDL particle size (P=0.0028), and increased mean HDL particle size (P<0.0001) compared to controls. No significant correlations were found between lipoprotein subclasses and arterial stiffness in T1D subjects.

Conclusions: T1D subjects have increased arterial stiffness when compared to controls, despite a less pro-atherogenic lipoprotein profile, indicating the need to identify other risk factors that correlate with arterial stiffness in T1D youth.”
“The development of an accessory breast tissue is attributed to the failure of regression of milk line remnants during embryogenesis. The accessory breasts can develop anywhere along the milk line, extending from axilla to the groin.

Results. Of the 172 patients, 75 (43.6%) developed angina (n=56) or ST-segment depression (n=30) during atropine administration. Eight of the 23 patients (35%) who underwent two tests exhibited scintigraphic

GSK1838705A ischemia (SDS >= 2) on only the test with atropine. Furthermore, the SDS was significantly greater on SPECT imaging with atropine (5.6 +/- 4.5 vs. 3.1 +/- 2.8; P=.0001).

Conclusions. One-third of patients who met scintigraphic criteria for ischemia at the end of submaximal exercise testing and after atropine administration would not have met those criteria without administration of the drug.”
“Hyperglycemic status may be rarely complicated by Epilepsia partialis continua (EPC) that usually responds to metabolic normalization. Anti-glutamic acid decarboxylase antibodies (GAD-Ab) play a pivotal role in the autoimmune process that leads to clinical onset of type 1 diabetes mellitus (T1DM). GAD-Ab have been recently reported in association with rare forms of refractory epilepsy, with or without association to T1DM. Here we describe a young patient who developed EPC five months after T1DM onset; GAD-Ab were detected in his cerebrospinal fluid with evidence of oligoclonal bands. His epileptic disorder evolved over time into drug-resistant epilepsy with continuous spike-waves during slow sleep and severe behavioral impairment. The

JQ1 solubility dmso role of both metabolic imbalance and GAD autoimmunity is discussed.”
“Cigarette smoking condensate (CSC) contains oxidant compounds able to generate superoxide. GANT61 datasheet The aim of the present study was to investigate the effect

of the exposure to CSC on: (1) free radical production, (2) the gene expression of the antioxidant enzymes Cu-Zn superoxide dismutase (SOD1), Mn superoxide dismutase (SOD2), Glutathione Peroxidase (GPx), and catalase (CAT), and (3) cell survival in human neuroblastoma SH-SY5Y cells. The results showed that exposure (24 h) to different concentrations (10-150 mu g/ml) of CSC caused a dose dependent cell injury that was coupled to the maximal increase of free radical production. These events were prevented by the addition to the incubation medium of the scavenger Vitamin E (50 mu M). Furthermore, CSC exposure caused a reduction of the gene expression of the antioxidant enzymes SOD1, SOD2, GPx, and CAT that was counteracted by Vitamin E (50 mu M). These results suggest that CSC exposure can induce a free radical overcharge that may be responsible for the inhibition of antioxidant enzymes expression and cell injury in SH-SY5Y human neuroblastoma cells. In fact the scavenger vitamin E can block both cell injury and inhibition of SOD1, SOD2, GPx, and CAT induced by CSC exposure.”
“Introduction and objectives. After cardiac surgery, temporary pacing leads are routinely implanted in the right ventricle (RV).